Working group Rickettsiology
The workgroup Rickettsiology deals with the detection of diseases caused by Rickettsiae. These bacteria are transmitted to humans and animals by arthropods, particularly ticks. Among others, Rickettsiae are the causative agents of Rocky Mountain spotted fever (R. rickettsii), different types of tick bite fever and Boutonneuse fever (R. conori). Another genus in the order Rickettsiales is Ehrlichia. This includes canine ehrlichiosis (tropical canine pancytopenia), an infectious disease caused by Ehrlichia canis, which affects monocytes and lymphocytes. The disease which occurs in tropical regions and the Mediterranean area poses a threat to dogs taken along by their owners on vacation trips to these regions. In humans, Anaplasma phagocytophilum causes a febrile disease (human granulocytic anaplasmosis), but the pathogen can also infect dogs (canine anaplasmosis), cats, horses, and ruminants.
Furthermore, the workgroup Rickettsiology also conducts research on other tick-borne diseases which are not caused by Rickettsiae. These include borreliosis (Lyme disease), babesiosis and Q fever (Coxiella burnetti). The causative agent of Lyme disease is a rod-shaped bacterium which affects skin, joints and nervous system and leads to redness of the skin (Erythema migrans), muscular pain and neuropathia. The most important transmitter is the castor bean tick (Ixodes ricinus). The causative agents of babesioses are protozoans parasitizing in the red blood cells of vertebrates. Babesia canis causes babesiosis in dogs, while B. divergens among others affects cattle (red water fever). Human babesiosis is caused by the species B. divergens and B. microti. Important transmitters are also hard ticks of the genus Ixodes.
For information on Q fever please refer to the website of the National Reference Laboratory for Q Fever.