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Institute of Molecular Pathogenesis (IMP)

Working group Infection and Immunology

Research area Poultry

In area of research „Poultry “, we deal with host-pathogen-interactions in the course of bacterial infections, as salmonellosis and chlamydiosis, in chicken and cattle. In in-vitro and in-vivo experiments, we analyse the host’s innate and acquired immune response in relation to the virulence of pathogens on molecular level. Of particular research interest are (i) the determination of special functions of granulocytes, macrophages and γδ T-cell subsets after vaccination and infection of birds and (ii) the molecular mechanisms of host adaption of different Chlamydophila species.

Methods

  • Immunohistology
  • Flow cytometry
  • Confocal Laser-scanning Microscopy (CLSM)
  • Quantitative real-time RT-PCR
  • Culture of primary cells
  • Projects 

Projects

  • BMBF-Project (2. part of 01 KI 0720)
    Subproject VII (01.01.2011 – 31.12.2013): Virulence factors and cell functions after infection with Chlamydophila strains of different host ranges
  • BMBF-Project (2. part of 01 KI 0720)
    Subproject II (01.09.2011 – 31.08.2014): The calf model of the Chlamydophila psittaci infection and its application for human research (subarea: Immunity)
  • EMIDA-ERA-NET-Project (HealthyGut; 01.04.2011-31.03.2014)
    Multi focal strategies to improve gut health and reduce enteritis in poultry and pigs (subarea: Immunity)